一、词义不同
full of
翻译：装满、盛满。
例句：The bottle is full of water. 瓶子装满了水。
fill with
翻译：被装满、被盛满。
例句：The bottle is filled with water. 瓶子被装满了水。
二、语境不同
full of 用于主动句。
例句：Whenever I feel upset I would go swimming and then I would be full of energy .
每当我感到难过时，我就会去游泳，然后我就会充满能量。
full with 用于被动句。
例句：Paid in full with one glass of milk.
医药费已由一杯牛奶支付。
三、文法不同
full of 属于宾补，就是宾语补足语，是用来补充说明宾语。
例句：See the book as a mine fullof ORE not GOLD.
将这本书看作是装满矿石的矿山，而不是黄金山。
full with 属于主补，就是主语补足语，用来补充说明主语。
例句：All that we owned and built and grew together, including our children, was
signed over to me in full with no strings attached.
我们的婚后所有东西，包括孩子，都完整地判给我了，没有任何附加条件。
