Dear Dr ***,
Please excuse me for taking some of your time.
We submitted a manuscript entitled “***” (Ref. No. ***) to *** on 25 Nov 2011. I do not know whether it is a proper time to contact you regarding the review process. We will be grateful for you if you tell us what has occurred to the review process of my manuscript in the last 5 months. I am looking forward to your early reply.
Sincerely yours